UNC 926 hydrochloride

Cat. No. 4516

UNC 926 hydrochloride C16H21BrN2O.HCl [1184136-10-4]

Price and Availability

For UNC 926 hydrochloride pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: (3-Bromophenyl)[4-(1-prrolidinyl)-1-piperidinyl]methanone hydrochloride

Biological Activity

Methyl-lysine (Kme) reader domain inhibitor; binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 μM). Selectively inhibits the L3MBTL13XMBT-H4K20me1 interaction in a peptide pull down assay.

Technical Data

M.Wt:
373.72
Formula:
C16H21BrN2O.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at RT
CAS No:
1184136-10-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Herold et al (2012) Structure-activity relationships of methyl-lysine reader antagonists. Med.Chem.Comm 3 45.

If you know of a relevant reference for UNC 926 hydrochloride please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses UNC 926 hydrochloride from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: UNC 926 hydrochloride, supplier, UNC926, Methyl-lysine, Kme, readers, antagonists, MBT, domains, L3MBTL1, histones, epigenetics, Tocris Bioscience, MBT Domain Inhibitor products

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

Epigenetics Toolbox

80 Epigenetic modulators supplied pre-dissolved in DMSO

Tocriscreen Epigenetics Toolbox

Includes many of the latest compounds available for epigenetics research. Covers a wide range of targets, such as bromodomains, KMTs, PRMTs and HDACs.

divider line

Epigenetics Scientific Review

Written by S. Müller-Knapp & P. Brown

Epigenetics Scientific Review

Our Epigenetics review gives an overview of the development of chemical probes for epigenetic targets, and discusses their biological effects. Request copy or view PDF today.

divider line

Epigenetics Research Bulletin

Epigenetics Research Bulletin

The epigenetics research bulletin gives an introduction into mechanisms of epigenetic regulation, and highlights key Tocris products for epigenetics targets. View PDF today.

divider line

New Products in this Area

OTX 015

BET bromodomain inhibitor; orally bioavailable

H3K4(Me2) (1-20)

Histone H3 peptide

TC AC 28

High affinity BET bromodomain ligand

Sign-up for new product e-alerts
divider line

Twitter Updates

Follow @Tocris on Twitter

Follow us on Twitter!

Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.