Cat. No. 4513
Chemical Name: 2-[((1,1'-Biphenyl)-4-ylamino)carbon
Biological ActivityPotently induces differentiation of human mesenchymal stem cells into chondrocytes (EC50 = 100 nM). Reduces disease severity in a mouse model of osteoarthritis; displays protective effects against osteoarthritic stimuli in mature chondrocytes in vitro.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Johnson et al (2012) A stem cell-based approach to cartilage repair. Science 336 717. PMID: 22491093.
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Keywords: Kartogenin, supplier, Supplier, mesenchymal, stem, cell, differentiation, differentiators, potently, inducers, chondrocytes, cartilage, osteoarthritis, Tocris Bioscience, Mesenchymal Stem Cells products
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November 8 - 10, 2017