Cat. No. 1516
Chemical Name: 4-[3-[(1,1-Dimethylethyl)amino]-2-h
Biological Activityβ-adrenoceptor and 5-HT1A/1B receptor antagonist. pKB/pA2 values are 8.3 and 8.0 for 5-HT1A and 5-HT1B receptors respectively. Centrally active following systemic administration in vivo.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Hoyer et al (1994) VII International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol.Rev. 46 157. PMID: 7938165.
Chojnacka-Wojcik and Przegalinski (1991) Evidence for the involvement of 5-HT1A receptors in the anticonflict effect of ipsapirone in rats. Neuropharmacology 30 703. PMID: 1681448.
Engel et al (1986) Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites. Naunyn-Schmied.Arch.Pharmacol. 332 1.
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Keywords: SDZ 21009, supplier, β-adrenoceptor, beta-adrenoceptor, b-adrenoceptor, antagonists, 5-HT1A/1B, β-adrenergic, beta-adrenergic, b-adrenergic, Receptors, Non-Selective, Serotonin, SDZ21009, Tocris Bioscience, Non-selective Adrenergic β Receptor Antagonist products
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