SDZ 21009

Cat. No. 1516

SDZ 21009 C19H28N2O4 [39731-05-0]

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Chemical Name: 4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-1H-indole-2-carboxylic acid, 1-methylethyl ester

Biological Activity

β-adrenoceptor and 5-HT1A/1B receptor antagonist. pKB/pA2 values are 8.3 and 8.0 for 5-HT1A and 5-HT1B receptors respectively. Centrally active following systemic administration in vivo.

Technical Data

M.Wt:
348.44
Formula:
C19H28N2O4
Solubility:
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Storage:
Store at RT
CAS No:
39731-05-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Hoyer et al (1994) VII International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol.Rev. 46 157. PMID: 7938165.

Chojnacka-Wojcik and Przegalinski (1991) Evidence for the involvement of 5-HT1A receptors in the anticonflict effect of ipsapirone in rats. Neuropharmacology 30 703. PMID: 1681448.

Engel et al (1986) Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites. Naunyn-Schmied.Arch.Pharmacol. 332 1.

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Keywords: SDZ 21009, supplier, β-adrenoceptor, beta-adrenoceptor, b-adrenoceptor, antagonists, 5-HT1A/1B, β-adrenergic, beta-adrenergic, b-adrenergic, Receptors, Non-Selective, Serotonin, SDZ21009, Tocris Bioscience, Non-selective Adrenergic β Receptor Antagonist products

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