Cat. No. 4475
Chemical Name: 6-Cyclohexyl-3-(2-furanyl)-1,2,4-tr
Biological ActivityWnt signaling modulator. Potently inhibits Wnt/β-catenin-dependent transcription in murine ES cells (EC50 = 23 nM) and zebrafish embryos. Enlarges heart size via cardiomyocyte hyperplasia; induces ES cell cardiac differentiation.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Ni et al (2011) Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling. Chem.Biol. 18 1658. PMID: 22195568.
If you know of a relevant reference for Cardionogen 1 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Cardionogen 1 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Cardionogen 1, supplier, Cardionogen1, Wnt/B-catenin, beta-catenin, β-catenin, embryonic, stem, cells, inhibitors, inhibits, cardiac, hyperplasia, differentiation, Tocris Bioscience, β-catenin products
Find multiple products by catalog number
New Products in this Area
Wnt signaling inhibitor; binds the PDZ domain of the Dishevelled (Dvl) protein
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.