Cardionogen 1

Cat. No. 4475

Cardionogen 1 C13H14N4OS [577696-37-8]

Price and Availability

For Cardionogen 1 pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole

Biological Activity

Wnt signaling modulator. Potently inhibits Wnt/β-catenin-dependent transcription in murine ES cells (EC50 = 23 nM) and zebrafish embryos. Enlarges heart size via cardiomyocyte hyperplasia; induces ES cell cardiac differentiation.

Technical Data

M.Wt:
274.34
Formula:
C13H14N4OS
Solubility:
Soluble to 20 mM in DMSO and to 10 mM in ethanol
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
577696-37-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Ni et al (2011) Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling. Chem.Biol. 18 1658. PMID: 22195568.

If you know of a relevant reference for Cardionogen 1 please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses Cardionogen 1 from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: Cardionogen 1, supplier, Cardionogen1, Wnt/B-catenin, beta-catenin, β-catenin, embryonic, stem, cells, inhibitors, inhibits, cardiac, hyperplasia, differentiation, Tocris Bioscience, β-catenin products

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

Wnt Pathway

Wnt Signaling Pathway

Signals through the Wnt pathway are fundamental for the regulation of cellular differentiation and proliferation. View pathway or download PDF today.

divider line

New Products in this Area

NSC 668036

Wnt signaling inhibitor; binds the PDZ domain of the Dishevelled (Dvl) protein

Sign-up for new product e-alerts
divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.