Cat. No. 4475
Chemical Name: 6-Cyclohexyl-3-(2-furanyl)-1,2,4-tr
Biological ActivityWnt signaling modulator. Potently inhibits Wnt/β-catenin-dependent transcription in murine ES cells (EC50 = 23 nM) and zebrafish embryos. Enlarges heart size via cardiomyocyte hyperplasia; induces ES cell cardiac differentiation.
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Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Ni et al (2011) Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling. Chem.Biol. 18 1658. PMID: 22195568.
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Keywords: Cardionogen 1, supplier, Cardionogen1, Wnt/B-catenin, beta-catenin, β-catenin, embryonic, stem, cells, inhibitors, inhibits, cardiac, hyperplasia, differentiation, Tocris Bioscience, β-catenin products