Cat. No. 4457
Chemical Name: 2-[3-Cyano-5-(3,4-dichlorophenyl)-4
Biological ActivityGPR35 agonist (EC50 = 32 nM in DMR assays). Also displays partial agonist activity in a β-arrestin translocation assay (EC50 = 10.2 μM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Deng et al (2011) Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists. J.Med.Chem. 54 7385. PMID: 21950657.
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Keywords: YE 120, supplier, YE120, gpr35, agonists, orphan, receptors, Tocris Bioscience, GPR35 Agonist products
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