Cat. No. 4455
Chemical Name: 1-[(2S)-3-Mercapto-2-methyl-1-oxopr
Biological ActivityAngiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.022 μM). Also displays reversible, competitive inhibition of leukotriene A4 (LTA4) hydrolase.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Fujita and Yoshikawa (1999) LKPNM: a prodrug-type ACE-inhibitory peptide derived from fish protein. Immunopharmacology. 44 123. PMID: 10604535.
Zhang et al (1996) Effects of early captopril treatment and its removal on plasma angiotensin converting enzyme (ACE) activity and arginine vasopressin in hypertensive rats (SHR) and normotensive rats (WKY). Clin.Exp.Hypertens. 18 201. PMID: 8869001.
Orning et al (1991) Inhibition of leukotriene A4 hydrolase/aminopeptidase by captopril. J.Biol.Chem. 266 16507. PMID: 1885582.
If you know of a relevant reference for Captopril please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Captopril from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Captopril, supplier, ACE, inhibitors, angiotensin-converting, enzyme, antihypertensives, LTA4, reversible, inhibits, peptidyl, dipeptidase, A, carboxycathepsin, Tocris Bioscience, Angiotensin-Converting Enzyme Inhibitor products
Find multiple products by catalog number
New Products in this Area
Plasminogen activator inhibitor-1 (PAI-1) inhibitorSB 3CT
Selective high affinity MMP2 inhibitor
August 20 - 24, 2017
Paris , France