Cat. No. 4447
Chemical Name: N-Methyl-N-[(3R)-3-phenyl-3-[4-(tri
Biological ActivityInhibitor of the glial glycine transporter (GlyT1); derivative of Org 24598 (Cat. No. 4035).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Chue et al (2013) Glycine reuptake inhibition as a new therapeutic approach in schizophrenia: focus on the glycine transporter 1 (GlyT1). Curr.Pharm.Des. 19 1311. PMID: 23194655.
Brown et al (2001) Discovery and SAR of org 24598-a selective glycine uptake inhibitor. Bioorg.Med.Chem.Lett. 11 2007. PMID: 11454468.
If you know of a relevant reference for Org 24598 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Org 24598 from Tocris? If so please let us know.
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Keywords: Org 24598, supplier, Org24598, glial, glycine, transporters, glyt1, inhibitors, inhibits, Tocris Bioscience, Glycine Transporter Inhibitor products