Cat. No. 4443
Chemical Name: (±)-2-Methylamino-1-(4-methylphenyl)
Biological ActivityInhibits striatal dopamine uptake and hippocampal 5-HT uptake in synaptosomes (IC50 values are 467 and 558 nM respectively). Administration causes a decrease in dopamine and 5-HT transporter function. Synthetic CNS stimulant; brain penetrant.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Hadlock et al (2011) 4-methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse. J.Pharmacol.Exp.Ther. 339 530. PMID: 21810934.
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Keywords: Mephedrone hydrochloride, supplier, inhibitors, inhibits, dopamine, da, 5-ht, serotonin, uptake, transporters, brain, penetrant, Tocris Bioscience, Dopamine Transporter Inhibitor products