Cat. No. 4443
Chemical Name: (±)-2-Methylamino-1-(4-methylphenyl)
Biological ActivityInhibits striatal dopamine uptake and hippocampal 5-HT uptake in synaptosomes (IC50 values are 467 and 558 nM respectively). Administration causes a decrease in dopamine and 5-HT transporter function. Synthetic CNS stimulant; brain penetrant.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Hadlock et al (2011) 4-methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse. J.Pharmacol.Exp.Ther. 339 530. PMID: 21810934.
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Keywords: Mephedrone hydrochloride, supplier, inhibitors, inhibits, dopamine, da, 5-ht, serotonin, uptake, transporters, brain, penetrant, Tocris Bioscience, Dopamine Transporter Inhibitor products
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