Mephedrone hydrochloride

Cat. No. 4443

Mephedrone hydrochloride C11H15NO.HCl [1189726-22-4]

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Chemical Name: (±)-2-Methylamino-1-(4-methylphenyl)propan-1-one hydrochloride

Biological Activity

Inhibits striatal dopamine uptake and hippocampal 5-HT uptake in synaptosomes (IC50 values are 467 and 558 nM respectively). Administration causes a decrease in dopamine and 5-HT transporter function. Synthetic CNS stimulant; brain penetrant.

Technical Data

M.Wt:
213.7
Formula:
C11H15NO.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
1189726-22-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Hadlock et al (2011) 4-methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse. J.Pharmacol.Exp.Ther. 339 530. PMID: 21810934.

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Keywords: Mephedrone hydrochloride, supplier, inhibitors, inhibits, dopamine, da, 5-ht, serotonin, uptake, transporters, brain, penetrant, Tocris Bioscience, Dopamine Transporter Inhibitor products

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