Cat. No. 4437
Chemical Name: 4-Butoxy-N-(2,4-difluorophenyl)benz
Biological ActivityPositive allosteric modulator of mGlu5 receptors (EC50 = 33 nM). Binds to a site distinct from that bound by MPEP (Cat. No. 1212).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Hammond et al (2010) Discovery of a novel chemical class of mGlu5 allosteric ligands with distinct modes of pharmacology. ACS Chem.Neurosci. 1 702. PMID: 20981342.
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Keywords: VU 0357121, supplier, VU0357121, pams, positive, allosteric, modulators, mglu5, receptors, mglur5, Tocris Bioscience, Glutamate (Metabotropic) Group I Receptor Modulator products
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