Lauryl-LF 11

Cat. No. 4422

Lauryl-LF 11 CH3-(CH2)10-CO-NH-Phe-Gln-Trp-Gln-Arg-Asn-Ile-Arg-Lys-Val-Arg-NH2

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Biological Activity

N-terminally acylated analog of LF 11 (Cat. No. 4421). Displays enhanced antibacterial and LPS-binding activities.

Technical Data

M.Wt:
1712.11
Formula:
C81H134N26O15
Sequence:
FQWQRNIRKVR

(Modifications: Phe-1 = CH3-(CH2)10-CO-NH-Phe, Arg-11 = C-terminal amide)

Solubility:
Soluble to 2 mg/ml in 30% acetonitrile / water
Storage:
Store at -20°C
CAS No:
832729-14-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Rosenfeld et al (2010) Effect of the hydrophobicity to net positive charge ratio on antibacterial and anti-endotoxin activities of structurally similar antimicrobial peptides. Biochemistry 49 853. PMID: 20058937.

Zweytick et al (2006) Influence of N-acylation of a peptide derived from human lactoferricin on membrane selectivity. Biochim.Biophys.Acta 1758 1426. PMID: 16616888.

Andra et al (2005) Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 385 135. PMID: 15344905.

If you know of a relevant reference for Lauryl-LF 11 please let us know.

Citations are publications that use Tocris products.

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Keywords: Lauryl-LF 11, supplier, lauryl-LF11, lps, lipopolysaccharide, lactoferricin, antimicrobial, peptides, antibiotics, Tocris Bioscience, Antibiotic products

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