LF 11

Cat. No. 4421

LF 11 Phe-Gln-Trp-Gln-Arg-Asn-Ile-Arg-Lys-Val-Arg-NH2

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Biological Activity

Peptide based on the lipopolysaccharide (LPS)-binding region of human lactoferricin. Neutralizes LPS; displays antimicrobial activity against Gram-negative and Gram-positive bacteria. Analog lauryl-LF 11 (Cat. No. 4422) available.

Technical Data


(Modifications: Arg-11 = C-terminal amide)

Soluble to 2 mg/ml in 20% acetonitrile / water
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Sanchez-Gomez et al (2008) Comparative analysis of selected methods for the assessment of antimicrobial and membrane-permeabilizing activity: a case study for lactoferricin derived peptides. BMC Mirobiol. 11 196. PMID: 19014450.

Andra et al (2005) Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 385 135. PMID: 15344905.

Japelj et al (2005) Structural origin of endotoxin neutralization and antimicrobial activity of a lactoferrin-based peptide. J.Biol.Chem. 280 16955. PMID: 15687491.

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View Related Products by Product Action

Keywords: LF 11, supplier, LF11, lps, lipopolysaccharide, lactoferricin, antimicrobial, peptide, antibiotics, Tocris Bioscience, Antibiotic products

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