Carbazeran citrate

Cat. No. 4420

Carbazeran citrate C18H24N4O4.C6H8O7 [153473-94-0]

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Chemical Name: Ethyl 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl carbamate citrate

Biological Activity

Aldehyde oxidase (AO) substrate. Exhibits activities as a phosphodiesterase inhibitor; produces concentration-dependent positive inotropic responses in isolated right atria.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Technical Data

Soluble to 50 mM in water and to 100 mM in DMSO
>98 %
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Hutzler et al (2011) Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes. Drug Metab.Dispos. 40 267. PMID: 22031625.

Shahid and Rodger et al (1989) Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition. Br.J.Pharmacol. 98 291. PMID: 2478244.

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Citations are publications that use Tocris products.

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View Related Products by Product Action

Keywords: Carbazeran citrate, supplier, Aldehyde, oxidases, AO, substrates, phosphodiesterase, inhibitors, inhibits, PDE, inotropic, Tocris Bioscience, Other Oxygenase/Oxidase products

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