Cat. No. 4419
Chemical Name: (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)
Biological ActivityMacrolide antibiotic. Active against multidrug resistant respiratory tract bacterial strains. Does not have the hepatotoxic side effects associated with telithromycin. Orally active.
Licensing InformationSold for research purposes under agreement from Pfizer Inc.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Zientek et al (2010) In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase. Drug Metab.Dispos. 38 1322. PMID: 20444863.
Magee et al (2009) Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections. J.Med.Chem. 52 7446. PMID: 19775168.
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Keywords: PF 945863, supplier, PF945863, macrolide, antibiotics, multidrug, resistant, respiratory, tract, bacterial, Tocris Bioscience, Antibiotic products
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