(S)-(+)-Ketamine hydrochloride

Cat. No. 4379

(S)-(+)-Ketamine hydrochloride C13H16ClNO.HCl [33643-47-9]

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Chemical Name: (S)-(+)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride

Biological Activity

NMDA receptor antagonist. Displays neuroprotective efficacy in vitro. Racemate (Cat. No. 3131) also available.

Technical Data

M.Wt:
274.19
Formula:
C13H16ClNO.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
33643-47-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Benrath et al (2005) Low dose of S(+)-ketamine prevents long-term potentiation in pain pathways under strong opioid analgesia in the rat spinal cord in vivo. Br.J.Anaesth. 95 518. PMID: 16113037.

Proescholdt et al (2001) Neuroprotection of S(+) ketamine isomer in global forebrain ischemia. Brain Res. 904 245. PMID: 11406122.

Ryder et al (1978) Comparative pharmacology of the optical isomers of ketamine in mice. Eur.J.Pharmacol. 49 15. PMID: 658124.

If you know of a relevant reference for (S)-(+)-Ketamine hydrochloride please let us know.

Citations are publications that use Tocris products.

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Keywords: (S)-(+)-Ketamine hydrochloride, supplier, nmda, nmdar, antagonists, Tocris Bioscience, Ketamine and Metabolite products

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