(S)-(+)-Ketamine hydrochloride

Cat. No. 4379

(S)-(+)-Ketamine hydrochloride C13H16ClNO.HCl [33643-47-9]

Price and Availability

For (S)-(+)-Ketamine hydrochloride pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: (S)-(+)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride

Biological Activity

NMDA receptor antagonist. Displays neuroprotective efficacy in vitro. Racemate (Cat. No. 3131) also available.

Technical Data

M.Wt:
274.19
Formula:
C13H16ClNO.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
33643-47-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Benrath et al (2005) Low dose of S(+)-ketamine prevents long-term potentiation in pain pathways under strong opioid analgesia in the rat spinal cord in vivo. Br.J.Anaesth. 95 518. PMID: 16113037.

Proescholdt et al (2001) Neuroprotection of S(+) ketamine isomer in global forebrain ischemia. Brain Res. 904 245. PMID: 11406122.

Ryder et al (1978) Comparative pharmacology of the optical isomers of ketamine in mice. Eur.J.Pharmacol. 49 15. PMID: 658124.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses (S)-(+)-Ketamine hydrochloride from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: (S)-(+)-Ketamine hydrochloride, supplier, nmda, nmdar, antagonists, Tocris Bioscience, NMDA Receptor Antagonist products

Quick Order

Find multiple products by catalog number

divider line

Pain Research Product Guide

Pain Research Product Guide

Our Pain guide highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

Neurodegeneration Research Product Guide

Neurodegeneration Product Guide

Our Neurodegeneration guide highlights over 275 products for neurodegeneration research. Request copy or view PDF today.

divider line

Learning and Memory

Written by Clea Warburton and Zafar Bashir

Learning & Memory Life Science Poster

Our Learning and Memory poster gives an overview of the cellular mechanisms underlying recognition memory and its links to long-term depression. Request copy or view PDF today.

divider line

Huntington's Disease: Pathophysiology and Clinical Prospects

Huntington's Disease Life Science Poster

Our Huntington's Disease (HD) poster summarizes the medium spiny neuron intracellular signaling pathways implicated in the pathology of HD. Request copy or view PDF today.

divider line

Therapeutic Strategies in Schizophrenia

Written by J. Lieberman

Schizophrenia Life Science Poster

Our Schizophrenia poster higlights the targets and pathways representing the most promising strategies to pursue for novel drug development. Request copy today.

divider line

Peripheral Sensitization

Written by Grant D. Nicol and Michael R. Vasko

Pain Life Science Poster

Our Peripheral Sensitization poster gives a summary of the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. Request copy or view PDF today.

divider line

Parkinson's disease: Neurobiology and Therapeutic Strategies

Written by Anthony H.V. Schapira

Parkinson's Life Science Poster

Our Parkinson's disease (PD) poster summarizes the neurobiology of the disease, and highlights current therapeutic treatments for symptomatic PD. Request copy or view PDF today.

divider line

Antidepressants - Current and Future Targets

Written by P. Skolnich et al

Depression Life Science Poster

Our Depression poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder. Request copy or view PDF today.

divider line

Alzheimer's Disease: Neurobiology and Drug Targets

Written by Alan Palmer

Alzheimer's Life Science Poster

Our Alzheimer's disease poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease. Request copy or view PDF today.

divider line

New Products in this Area

(S)-Norketamine hydrochloride

NMDA receptor modulator; metabolite of Ketamine hydrochloride (Cat. No.3131)

2S,6S-Hydroxynorketamine hydrochloride

Potent AMPA agonist; antidepressant

2R,6R-Hydroxynorketamine hydrochloride

Potent AMPA agonist; lacks ketamine-related side effects

(R)-Norketamine hydrochloride

NMDA receptor modulator; metabolite of Ketamine hydrochloride (Cat. No.3131).

PEAQX tetrasodium salt

Potent NMDA receptor antagonist; NR2A selective

Sign-up for new product e-alerts
divider line

AACR 2017

Win a $1,000 travel grant

AACR travel Grant 2017

Bio-Techne is offering 10 travel grants of $1,000 for AACR 2017.