Cat. No. 4378
Chemical Name: (7R)-4-Hydroxy-N,N,N-trimethyl-10-o
Biological ActivitySelective agonist of the orphan nuclear receptor LRH-1 (liver receptor homolog-1, NR5A2) in vitro. Induces bile acid biosynthetic enzymes; increases bile acid and decreases hepatic triglycerides and serum glucose. Exhibits antidiabetic effects.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Lee et al (2011) A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Nature 474 506. PMID: 21614002.
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Keywords: DLPC, supplier, Dilauroyl, phosphatidylcholine, LRH-1, agonist, orphan, nuclear, receptor, agonists, NR5A2, saturated, fatty, acid, chain, liver, receptor, homolog, homologue, Tocris Bioscience, Other Lipid Metabolism products
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December 13 - 15, 2016