Cat. No. 4375
Chemical Name: 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3
Biological ActivitySelective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes; blocks cell proliferation. Enhancer of rapamycin (Cat. No. 1292).
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Certificate of Analysis / Product Datasheet / Safety Data Sheet
Aghajanyy et al (2010) Chemical genetics of TOR identifies an SCF family E3 ubiquitin ligase inhibitor. Nat.Biotechnol. 28 738. PMID: 20581845.
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Keywords: SMER 3, supplier, SMER3, ubiquitin, E3, ligase, inhibitors, inhibits, Ub, ligases, small-molecule, enhancers, rapamycin, SCF, family, Tocris Bioscience, Ubiquitin E3 Ligase Inhibitor products