Cat. No. 4375
Chemical Name: 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3
Biological ActivitySelective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes; blocks cell proliferation. Enhancer of rapamycin (Cat. No. 1292).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Aghajanyy et al (2010) Chemical genetics of TOR identifies an SCF family E3 ubiquitin ligase inhibitor. Nat.Biotechnol. 28 738. PMID: 20581845.
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Keywords: SMER 3, supplier, SMER3, ubiquitin, E3, ligase, inhibitors, inhibits, Ub, ligases, small-molecule, enhancers, rapamycin, SCF, family, Tocris Bioscience, Ubiquitin E3 Ligase Inhibitor products
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