Cat. No. 4352
Chemical Name: 1,3-Dihydro-N,3,3-trimethyl-1-pheny
Biological ActivitySelective noradrenalin re-uptake inhibitor; exhibits a high affinity for the human noradrenalin transporter (NET) against SERT and DAT (IC50 values are 0.79, 850 and 9300 nM for inhibition of monoamine uptake by NET, SERT and DAT respectively). Antidepressant.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Schou et al (2006) Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram. Mol.Imaging Biol. 8 1.
McConathy et al (2004) Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporter. Nucl.Med.Biol. 31 (6) 705. PMID: 15246361.
Rowlett et al (2004) Cocaine-like discriminative stimulus effects of heroin: modulation by selective monoamine transport inhibitors. J.Pharmacol.Exp.Ther. 310 342. PMID: 14985417.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Talsupram hydrochloride from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Talsupram hydrochloride, supplier, norepinephrine, reuptake, inhibitors, inhibits, noradrenaline, noradrenalin, transporters, NET, antidepressants, selective, Tocris Bioscience, Adrenergic Transporter Inhibitor products
Find multiple products by catalog number
New Products in this Area
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.