Cat. No. 4345
Chemical Name: [2-(2,4-Dichlorophenyl)-6-fluoro-2-
Biological ActivityPotent, high affinity CB1 receptor inverse agonist (EC50 = 11 nM in cAMP assay; Ki = 4 nM). Demonstrates high efficacy in a hypothermia assay (ID50 = 5 mg/kg) in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Alig et al (2008) Benzodioxoles: novel cannabinoid-1 receptor inverse agonists for the treatment of obesity. J.Med.Chem. 51 2115. PMID: 18335976.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses TC-C 14G from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: TC-C 14G, supplier, TC-C14G, cannabinoid, CB1, receptor, inverse, agonists, potent, high, affinity, Tocris Bioscience, CB1 Receptor Antagonist products
Find multiple products by catalog number
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.