Cat. No. 4345
Chemical Name: [2-(2,4-Dichlorophenyl)-6-fluoro-2-
Biological ActivityPotent, high affinity CB1 receptor inverse agonist (EC50 = 11 nM in cAMP assay; Ki = 4 nM). Demonstrates high efficacy in a hypothermia assay (ID50 = 5 mg/kg) in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Alig et al (2008) Benzodioxoles: novel cannabinoid-1 receptor inverse agonists for the treatment of obesity. J.Med.Chem. 51 2115. PMID: 18335976.
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Keywords: TC-C 14G, supplier, TC-C14G, cannabinoid, CB1, receptor, inverse, agonists, potent, high, affinity, Tocris Bioscience, CB1 Receptor Antagonist products