Cat. No. 4345
Chemical Name: [2-(2,4-Dichlorophenyl)-6-fluoro-2-
Biological ActivityPotent, high affinity CB1 receptor inverse agonist (EC50 = 11 nM in cAMP assay; Ki = 4 nM). Demonstrates high efficacy in a hypothermia assay (ID50 = 5 mg/kg) in vivo.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Alig et al (2008) Benzodioxoles: novel cannabinoid-1 receptor inverse agonists for the treatment of obesity. J.Med.Chem. 51 2115. PMID: 18335976.
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Keywords: TC-C 14G, supplier, TC-C14G, cannabinoid, CB1, receptor, inverse, agonists, potent, high, affinity, Tocris Bioscience, CB1 Receptor Antagonist products