Tertiapin LQ

Cat. No. 4339

Tertiapin LQ Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-Leu-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2 (Disulfide bridges: 3 - 14, 5 - 18)

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Biological Activity

Blocker of Kir1.1 channels; displays >250-fold selectivity for Kir1.1 (Kd values are 1.1, 274 and 361 nM for Kir1.1, Kir3.1/3.2 and Kir3.1/3.4 respectively). Derivative of tertiapin-Q (Cat. No. 1316).

Technical Data


(Modifications: Disulfide bridge between 3 - 14, 5 - 18, Lys-21 = C-terminal amide)

Soluble to 2 mg/ml in 20% acetonitrile / water
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Ramu et al (2008) Engineered specific and high-affinity inhibitor for a subtype of inward-rectifier K+ channels. Proc.Natl.Acad.Sci.USA 105 10774. PMID: 18669667.

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Keywords: Tertiapin LQ, supplier, TertiapinLQ, kir1.1, blockers, selective, Tocris Bioscience, Inward Rectifier Potassium (Kir) Channel Blocker products

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