NSC 33994

Cat. No. 4338

NSC 33994 C28H42N2O2 [82058-16-0]

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Chemical Name: E-4,4'-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]phenol

Biological Activity

Selective inhibitor of JAK2 (IC50 = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM.

Technical Data

M.Wt:
438.65
Formula:
C28H42N2O2
Solubility:
Soluble to 5 mM in DMSO with gentle warming and to 10 mM in ethanol with gentle warming
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
82058-16-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Kiss et al (2009) Identification of a novel inhibitor of JAK2 tyrosine kinase by structure-based virtual screening. Bioorg.Med.Chem.Lett. 19 3598. PMID: 19447617.

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Keywords: NSC 33994, supplier, NSC33994, jak2, janus, tyrosine, kinase, inhibitors, inhibits, Tocris Bioscience, JAK Inhibitor products

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