AR-M 1000390 hydrochloride

Cat. No. 4335

AR-M 1000390 hydrochloride C23H28N2O.HCl [209808-47-9]

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Chemical Name: N,N-Diethyl-4-(phenyl-4-piperidinylidenemethyl)-benzamide hydrochloride

Biological Activity

Non-peptidic, low-internalizing δ-selective opioid receptor agonist; derivative of SNC 80 (Cat. No. 0764). Does not trigger acute desensitization of the analgesic response; reduces CFA-induced hyperalgesia. Brain penetrant following systemic administration.

Technical Data

M.Wt:
384.94
Formula:
C23H28N2O.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>97 %
Storage:
Store at -20°C
CAS No:
209808-47-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Pradhan et al (2010) Ligand-directed trafficking of the δ-opioid receptor in vivo: Two paths toward analgesic tolerance. J.Neurosci. 30 16459. PMID: 21147985.

Marie et al (2003) Pharmacological characterization of AR-M1000390 at human opioid delta receptors. Life Sci. 73 1691. PMID: 12875901.

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Keywords: AR-M 1000390 hydrochloride, supplier, AR-M1000390, HCl, delta, opioids, δ-opioid, receptors, agonists, Tocris Bioscience, δ Opioid Receptor Agonist products

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