AR-M 1000390 hydrochloride
Cat. No. 4335
Chemical Name: N,N-Diethyl-4-(phenyl-4-piperidinyl
Biological ActivityNon-peptidic, low-internalizing δ-selective opioid receptor agonist; derivative of SNC 80 (Cat. No. 0764). Does not trigger acute desensitization of the analgesic response; reduces CFA-induced hyperalgesia. Brain penetrant following systemic administration.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Pradhan et al (2010) Ligand-directed trafficking of the δ-opioid receptor in vivo: Two paths toward analgesic tolerance. J.Neurosci. 30 16459. PMID: 21147985.
Marie et al (2003) Pharmacological characterization of AR-M1000390 at human opioid delta receptors. Life Sci. 73 1691. PMID: 12875901.
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Keywords: AR-M 1000390 hydrochloride, supplier, AR-M1000390, HCl, delta, opioids, δ-opioid, receptors, agonists, Tocris Bioscience, δ Opioid Receptor Agonist products