AR-M 1000390 hydrochloride
Cat. No. 4335
Chemical Name: N,N-Diethyl-4-(phenyl-4-piperidinyl
Biological ActivityNon-peptidic, low-internalizing δ-selective opioid receptor agonist; derivative of SNC 80 (Cat. No. 0764). Does not trigger acute desensitization of the analgesic response; reduces CFA-induced hyperalgesia. Brain penetrant following systemic administration.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Pradhan et al (2010) Ligand-directed trafficking of the δ-opioid receptor in vivo: Two paths toward analgesic tolerance. J.Neurosci. 30 16459. PMID: 21147985.
Marie et al (2003) Pharmacological characterization of AR-M1000390 at human opioid delta receptors. Life Sci. 73 1691. PMID: 12875901.
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