PSB 0777 ammonium salt
Cat. No. 4334
Chemical Name: 4-[2-[(6-Amino-9-b-D-ribofuranosyl-
Biological ActivityPotent adenosine A2A receptor full agonist (Ki = 44.4 nM for rat brain striatal A2A receptors). Exhibits subtype selectivity for A2A receptors over A1, A2B and A3 receptors (Ki ≥ 10 000 nM for rat A1, human A2B and human A3 receptors). Potentiates acetylcholine-induced contractions in ex vivo rat ileum/jejunum segments.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
El-Tayeb et al (2012) Development of polar adenosine A2A receptor agonists for inflammatory bowel disease: synergism with A2B antagonists. ACS Med.Chem.Lett. 2 890.
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