RP 001 hydrochloride
Cat. No. 4289
Chemical Name: N-[4-[5-[3-Cyano-4-(1-methylethoxy)
Biological ActivityPotent agonist of S1P1 receptors (EC50 = 9 pM). Induces internalization and polyubiquitination of S1P1 in vitro. Selective for S1P1 over S1P2 - S1P4.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Cahalan et al (2011) Actions of a picomolar short-acting S1P1 agonist in S1P1-eGFP knock-in mice. Nat.Chem.Biol. 7 254. PMID: 21445057.
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Keywords: RP 001 hydrochloride, supplier, RP001, sphingosine, 1, phosphate, s1p1, receptors, agonists, selective, Tocris Bioscience, Sphingosine-1-Phosphate Receptor Agonist products
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