MRS 2957 triethylammonium salt

Cat. No. 4260

MRS 2957 triethylammonium salt C19H28N5O20P3.3(C2H5)3N [1228271-30-4]

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Chemical Name: P1-[5'(N4-Methoxycytidyl)]-P3-(5'-uridyl)-triphosphate tri(triethylammonium) salt

Biological Activity

Potent P2Y6 agonist (EC50 = 12 nM). Displays 14- and 66-fold selectivity against P2Y2 and P2Y4 receptors respectively.

Technical Data

Soluble in water (supplied pre-dissolved at a concentration of 10mM)
>99 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Maruoka et al (2010) Pyrimidine ribonucleotides with enhanced selectivity as P2Y6 receptor agonists: novel 4-alkyloxyimino, (S)-methanocarba, and 5'-triphosphate γ-ester modifications. J.Med.Chem. 53 4488. PMID: 20446735.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for MRS 2957 triethylammonium salt include:

Balasubramanian et al (2014) Enhancement of glucose uptake in mouse skeletal muscle cells and adipocytes by P2Y6 receptor agonists. Nat Methods 9 e116203. PMID: 25549240.

Do you know of a great paper that uses MRS 2957 triethylammonium salt from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: MRS 2957 triethylammonium salt, supplier, MRS2957, triethylammonium, salt, potent, selective, purinergics, purines, purinoceptors, p2y6, agonists, Tocris Bioscience, Purinergic (P2Y) Receptor Agonist products

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