Cat. No. 4252
Chemical Name: (1-Methyl-3-[1-methyl-5-(4-methylph
Biological ActivityPotent and selective inhibitor of CYP3A4 (IC50 values are 0.03, 17 and 70 μM for CYP3A4, CYP3A5 and CYP3A7 respectively).
Licensing InformationSold for research purposes under agreement from Pfizer Inc.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Walsky et al (2012) Selective mechanism-based inactivation of cytochrome P4503A4 by cyp3cide (PF-04981517) and its utility as an in vitro tool for delineating the relative roles of cytochrome P4503A4 versus P4503A5 in the metabolism of drugs. Am.Soc.Pharmacol.Exp.Ther. Epub ahead of print.
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Citations are publications that use Tocris products.
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Keywords: PF 4981517, supplier, pfizer, PF4981517, selective, inhibitors, inhibits, cyp3a4, cytochrome, p4503A4, cyp3cide, Tocris Bioscience, Cytochrome P450 Inhibitor products
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