Cat. No. 4227
Chemical Name: N-(3-Hydroxypropyl)-5-methyl-1-[-4-
Biological ActivitySelective inhibitor of LFA-1 (lymphocyte function-associated antigen-1) adhesion to soluble intercellular adhesion molecule (sICAM) (IC50 = 5 μM in HL60 cells).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Sanfilippo et al (1995) Novel thiazole based heterocycles as inhibitors of LFA-1/ICAM-1 mediated cell adhesion. J.Med.Chem. 38 1057. PMID: 7707308.
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Keywords: RWJ 50271, supplier, RWJ50271, inhibitors, inhibits, LFA-1/ICAM-1, adhesion, sICAM, lymphocyte, function-associated, antigen-1, Tocris Bioscience, Integrin products
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