Cat. No. 4220
Chemical Name: 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-
Biological ActivityAdenosine receptor antagonist (Ki values are 42, 68 and 1130 nM for A1, A2B and A2A receptors).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Thummler and Dunwiddie (2000) Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism. J.Neurophysiol. 83 1787. PMID: 10758091.
Sebastiao et al (1990) The inhibitory adenosine receptor at the neuromuscular junction and hippocampus of the rat: antagonism by 1,3,8-substituted xanthines. Br.J.Pharmacol. 101 453. PMID: 2257444.
Jarvis et al (1989) Autoradiographic characterization of high-affinity adenosine A2 receptors in the rat brain. Brain Res. 484 111. PMID: 2713675.
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Citations are publications that use Tocris products.
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Keywords: XCC, supplier, XCC, adenosine, antagonists, Tocris Bioscience, Non-selective Adenosine Antagonist products
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