Cat. No. 4218
Chemical Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy
Biological ActivityFP prostaglandin receptor agonist. Exhibits submicromolar affinity for DP, EP, IP and TP receptors. Stimulates intracellular Ca2+ mobilization. Ocular hypotensive agent.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Hellberg et al (2001) Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. J.Ocul.Pharmacol.Ther. 17 421. PMID: 11765147.
Sharif et al (1999) [3H]AL-5848 ([3H]9beta-(+)-Fluprostenol). Carboxylic acid of travoprost (AL-6221), a novel FP prostaglandin to study the pharmacology and autoradiographic localization of the FP receptor. J.Pharm.Pharmacol. 51 685. PMID: 10454045.
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Keywords: Travaprost, supplier, Supplier, Travoprost, FP, receptor, agonist, prostaglandin, F2a, F2alpha, prostaglandin, ocular, hypotensive, Tocris Bioscience, Prostanoid Receptor Agonist products
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