EMDT oxalate

Cat. No. 4209

EMDT oxalate C15H22N2O.C2H2O4 [263744-72-5]

Price and Availability

For EMDT oxalate pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 2-Ethyl-5-methoxy-N,N-dimethyl-1H-indole-3-ethanamine oxalate

Biological Activity

Selective 5-HT6 agonist (with a Ki value of 16 nM at human 5-HT6 receptors). Exhibits potency comparable to serotonin for the activation of adenylate cyclase. Displays antidepressant-like effects.

Technical Data

Soluble to 50 mM in water and to 100 mM in DMSO
>98 %
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Svenningsson et al (2007) Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation. J.Neurosci. 27 4201. PMID: 17428998.

Glennon et al (2000) 2-Substituted tryptamines: Agents with selectivity for 5-HT6 serotonin receptors. J.Med.Chem. 43 1011. PMID: 10715164.

If you know of a relevant reference for EMDT oxalate please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses EMDT oxalate from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: EMDT oxalate, supplier, EMDT, oxalate, 5ht6, 5-HT6, agonist, agonists, serotonin-6, Tocris Bioscience, 5-HT6 Receptor Agonist products

Quick Order

Find multiple products by catalog number

divider line

Neurodegeneration Research Product Guide

Neurodegeneration Product Guide

Our Neurodegeneration guide highlights over 275 products for neurodegeneration research. Request copy or view PDF today.

divider line

GPCR Product Listing

GPCR Product Listing

Highlights over 450 products for GPCRs. Request copy or view PDF today.

divider line

5-HT Scientific Review

Written by N. Barnes & J. Neumaler

5-HT Receptors Scientific Review

Our 5-HT review summarizes the serotonin receptor subtypes and highlights their importance in mediating various physiological & pharmacological processes. Request copy or view PDF today.

divider line

Alzheimer's Life Science Poster

Written by Alan Palmer

Alzheimer's Life Science Poster

Our Alzheimer's disease poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease. Request copy or view PDF today.

divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.