Cat. No. 4209
Chemical Name: 2-Ethyl-5-methoxy-N,N-dimethyl-1H-i
Biological ActivitySelective 5-HT6 agonist (with a Ki value of 16 nM at human 5-HT6 receptors). Exhibits potency comparable to serotonin for the activation of adenylate cyclase. Displays antidepressant-like effects.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Svenningsson et al (2007) Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation. J.Neurosci. 27 4201. PMID: 17428998.
Glennon et al (2000) 2-Substituted tryptamines: Agents with selectivity for 5-HT6 serotonin receptors. J.Med.Chem. 43 1011. PMID: 10715164.
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Keywords: EMDT oxalate, supplier, EMDT, oxalate, 5ht6, 5-HT6, agonist, agonists, serotonin-6, Tocris Bioscience, 5-HT6 Receptor Agonist products