Cat. No. 4204
Chemical Name: 2-(2-Pyridinyl)-4H-1,3-benzothiazin
Biological ActivityMacrophage migration inhibitory factor (MIF) binder (Kd = 68.6 nM). Activates antioxidant response element (ARE)-mediated gene expression. Suppresses oxidative stress-induced cardiomyocyte apoptosis in vitro. Cardioprotective.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Kimura et al (2010) BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitor factor regulates ARE-mediated gene expression. Chem.Biol. 17 1282. PMID: 21168764.
If you know of a relevant reference for BTZO 1 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses BTZO 1 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: BTZO 1, supplier, BTZO1, mif, macrophage, migration, inhibitory, factors, binders, binds, cardioprotective, Tocris Bioscience, Cytokine products
Find multiple products by catalog number
New Products in this Area
Receptor for advanced glycation end products (RAGE) antagonistGaliellalactone
STAT3 inhibitor; active in vivoCP 424174
Inhibitor of IL-1β post-translational processing; indirectly inhibits NLRP3IT 901
NF-κB c-Rel subunit inhibitor
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.