Cat. No. 4184
Chemical Name: (2R,4S)-4-[[[3,5-bis(Trifluoromethy
Biological ActivityInhibitor of cholesteryl ester transfer protein (CETP). Also impairs endothelial function in vivo; induces hypertension and inhibits acetylcholine-induced vasodilation in rabbit central ear artery.
Licensing InformationSold for research purposes under agreement from Pfizer Inc.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Connelly et al (2010) Torcetrapib produces endothelial dysfunction independent of cholesteryl ester transfer protein inhibition. J.Cardiovascular Pharmacol. 55 459. PMID: 20051879.
Forrest et al (2008) Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increasing circulating levels of aldosterone. Br.J.Pharmacol. 154 1465. PMID: 18536749.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Torcetrapib from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: Torcetrapib, supplier, hypercholesterolemia, inhibits, cholesteryl, ester, transferase, protein, CETP, impairs, endothelial, function, Tocris Bioscience, Other Lipid Metabolism Inhibitor products
Find multiple products by catalog number
New Products in this Area
Acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor
September 14, 2016