Cat. No. 4169
Chemical Name: N-[4-(2-Hydroxyethyl)phenyl]-2-[(4-
Biological ActivitySelective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Pick et al (2010) Specific inhibitors of the breast cancer resistance protein (BCRP). ChemMedChem 5 1498. PMID: 20632361.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses KS 176 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: KS 176, supplier, KS176, selective, inhibitors, inhibits, breast, cancer, resistance, protein, BCRP, multidrug, transporter, ATP-binding, cassettes, Tocris Bioscience, Multidrug Transporter Inhibitor products
Find multiple products by catalog number
New Products in this Area
Potent P-glycoprotein (P-gp) inhibitorCeefourin 1
Selective MRP4 inhibitor
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.