Cat. No. 4169
Chemical Name: N-[4-(2-Hydroxyethyl)phenyl]-2-[(4-
Biological ActivitySelective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Pick et al (2010) Specific inhibitors of the breast cancer resistance protein (BCRP). ChemMedChem 5 1498. PMID: 20632361.
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Keywords: KS 176, supplier, KS176, selective, inhibitors, inhibits, breast, cancer, resistance, protein, BCRP, multidrug, transporter, ATP-binding, cassettes, Tocris Bioscience, Multidrug Transporter Inhibitor products