Cat. No. 4159
Alternative Name: 1-Hydroxycholecalciferol
Chemical Name: (1α,3β,5Z,7E)-9,10-Secocholesta-5,7,1
Biological ActivityMetabolite and prodrug of vitamin D3 (Cat. No. 4156). Improves mechanical bone strength and bone mass; suppresses osteoclastic bone resorption in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Shiraishi et al (2000) Alfacalcidol inhibits bone resorption and stmulates formation in an ovariectomized rat model of osteoporosis: Distinct actions from estrogen. Journal of Bone and Mineral Research. 15 770.
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Citations are publications that use Tocris products.
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Keywords: Alfacalcidol, supplier, VDR, activators, vitamin, D3, analogue, analog, receptors, Tocris Bioscience, Vitamin D Receptor products
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