Alfacalcidol

Cat. No. 4159

Alfacalcidol C27H44O2 [41294-56-8]

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Alternative Name: 1-Hydroxycholecalciferol

Chemical Name: (1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol

Biological Activity

Metabolite and prodrug of vitamin D3 (Cat. No. 4156). Improves mechanical bone strength and bone mass; suppresses osteoclastic bone resorption in vivo.

Technical Data

M.Wt:
400.64
Formula:
C27H44O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>97 %
Storage:
Store at -20°C
CAS No:
41294-56-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Shiraishi et al (2000) Alfacalcidol inhibits bone resorption and stmulates formation in an ovariectomized rat model of osteoporosis: Distinct actions from estrogen. Journal of Bone and Mineral Research. 15 770.

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Keywords: Alfacalcidol, supplier, VDR, activators, vitamin, D3, analogue, analog, receptors, Tocris Bioscience, Vitamin D Receptor products

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