Cat. No. 4157
Chemical Name: (1α,3β,5Z,7E,24R)-9,10-Secocholesta-5
Biological ActivitySynthetic vitamin D3 (Cat. No. 4156) analog. Promotes normal bone development by regulating calcium. Modulates immunological and inflammatory processes; induces nerve growth factor production in epidermal keratinocytes.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Rostowska-Nadolska et al (2010) Vitamin D derivatives: calcitriol and tacalcitol inhibits interleukin-6 and interleukin-8 expression in human nasal polyp fibroblasts. Adv.Med.Sci. 55 86. PMID: 20439185.
Fukuoka et al (2001) Tacalcitol, an active vitamin D3, induces nerve growth factor in human epidermal keratinocytes. Skin Pharmacol.Appl.Skin Physiol. 14 226. PMID: 11464105.
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Citations are publications that use Tocris products.
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Keywords: Tacalcitol, supplier, Tacalcitol, VDR, receptor, vitamin, D3, calcitrol, analogue, bone, Tocris Bioscience, Vitamin D Receptor products
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