Tacalcitol

Cat. No. 4157

Tacalcitol C27H44O3 [57333-96-7]

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Chemical Name: (1α,3β,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol

Biological Activity

Synthetic vitamin D3 (Cat. No. 4156) analog. Promotes normal bone development by regulating calcium. Modulates immunological and inflammatory processes; induces nerve growth factor production in epidermal keratinocytes.

Technical Data

M.Wt:
416.64
Formula:
C27H44O3
Solubility:
Soluble in DMSO and in ethanol
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
57333-96-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Rostowska-Nadolska et al (2010) Vitamin D derivatives: calcitriol and tacalcitol inhibits interleukin-6 and interleukin-8 expression in human nasal polyp fibroblasts. Adv.Med.Sci. 55 86. PMID: 20439185.

Fukuoka et al (2001) Tacalcitol, an active vitamin D3, induces nerve growth factor in human epidermal keratinocytes. Skin Pharmacol.Appl.Skin Physiol. 14 226. PMID: 11464105.

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Keywords: Tacalcitol, supplier, Tacalcitol, VDR, receptor, vitamin, D3, calcitrol, analogue, bone, Tocris Bioscience, Vitamin D Receptor products

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