Cat. No. 4157
Chemical Name: (1α,3β,5Z,7E,24R)-9,10-Secocholesta-5
Biological ActivitySynthetic vitamin D3 (Cat. No. 4156) analog. Promotes normal bone development by regulating calcium. Modulates immunological and inflammatory processes; induces nerve growth factor production in epidermal keratinocytes.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Rostowska-Nadolska et al (2010) Vitamin D derivatives: calcitriol and tacalcitol inhibits interleukin-6 and interleukin-8 expression in human nasal polyp fibroblasts. Adv.Med.Sci. 55 86. PMID: 20439185.
Fukuoka et al (2001) Tacalcitol, an active vitamin D3, induces nerve growth factor in human epidermal keratinocytes. Skin Pharmacol.Appl.Skin Physiol. 14 226. PMID: 11464105.
If you know of a relevant reference for Tacalcitol please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Tacalcitol from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: Tacalcitol, supplier, Tacalcitol, VDR, receptor, vitamin, D3, calcitrol, analogue, bone, Tocris Bioscience, Vitamin D Receptor products
Find multiple products by catalog number
New Products in this Area
Synthetic progesterone analogC-DIM 12
Nurr1 activator; inhibits NF-κB-dependent gene expression(S)-Equol
Potent estrogen receptor β (ERβ) agonistAilanthone
Potent inhibitor of androgen receptor (AR)(±)-ML 209
RORγt inverse agonist; suppresses Th17 cell differentiationAGN 193109
High affinity pan-RAR antagonistSR 9243
Selective LXR inverse agonist
July 8 - 12, 2017