Cat. No. 4141
Chemical Name: [2-[(4-Fluorophenyl)amino]-4-methyl
Biological ActivityAllosteric potentiator of α7, α4β2 and α4β4 nAChRs; displays selectivity against α3β4 nAChRs. Thought to potentiate agonist-evoked α7 responses by binding within the nAChR transmembrane region.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Young et al (2008) Potentiation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc.Natl.Acad.Sci. 105 14686.
Broad et al (2006) Identification and pharmacological profile of a new class of selective nicotinic acetylcholine receptor potentiators. J.Pharmacol.Exp.Ther. 318 1108. PMID: 16738207.
If you know of a relevant reference for LY 2087101 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses LY 2087101 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: LY 2087101, supplier, allosteric, potentiators, modulators, nicotinic, acetylcholine, receptors, nAChRs, alpha7, α7, a7, LY2087101, Tocris Bioscience, Nicotinic (α7) Receptor Modulator products