G418 disulfate salt
Cat. No. 4131
Biological ActivityAminoglycosidic antibiotic. Inhibits protein synthesis in both prokaryotic and eukaryotic cells. Used for selection of eukaryotic cells transfected with the neo gene.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Burke and Mogg (1985) Suppression of a nonsense mutation in mammalian cells in vivo by the aminoglycoside antibiotics G-418 and paromomycin. Nucleic Acids Res. 13 6265. PMID: 2995924.
Bar-Nun et al (1983) G-418, an elongation inhibitor of 80 S ribosomes. Biochim.Biophys.Acta. 741 123. PMID: 6193810.
Wagman et al (1974) Antibiotic G-418, a new Micromonospora-produced aminoglycoside with activity against protozoa and helminths: fermentation, isolation and preliminary characterization. Antimicrob.Agents Chemother. 6 144. PMID: 15828184.
If you know of a relevant reference for G418 disulfate salt please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses G418 disulfate salt from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: G418 disulfate salt, supplier, antibiotics, neomycin, resistance, cell, culture, aminoglycoside, inhibitors, inhibits, protein, synthesis, eukaryotes, eukaryotic, prokaryotes, prokaryotic, Tocris Bioscience, DNA, RNA and Protein Synthesis Inhibitor products
Find multiple products by catalog number
New Products in this Area
RAD51 recombinase inhibitorPCNA I1
PCNA inhibitorPladienolide B
mRNA splicing inhibitor; antitumorLin28 1632
RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.