Cat. No. 4120
Chemical Name: 4,8-Dihydroxyquinoline-2-carboxylic
Biological ActivityShown to selectively activate group II mGlu receptors in transfected HEK293 cells at nanomolar concentrations. Attenuates cAMP formation in mouse cortical slices expressing mGlu2 and mGlu3 receptors.
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Mauro et al (2010) Xanthurenic acid, a novel endogenous ligand for metabotropic glutamate receptors. Program No. 643.1/F2. 2010 Neuroscience Meeting Pl 2010 (Online).
Han et al (2007) The tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesis. J.Insect.Physiol. 53 254. PMID: 17070835.
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Keywords: Xanthurenic acid, supplier, metabotropic, glutamate, receptors, mGlu, ligands, group, II, 2, mglu2, mglu3, Tocris Bioscience, Glutamate (Metabotropic) Group II Receptor Activator products