GSK 9027

Cat. No. 4116

GSK 9027 C27H19F4N3O2S [1229096-88-1]

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Chemical Name: N-[4-[1-(4-Fluorophenyl)-1H-indazol-5-yl-3-(trifluoromethyl)phenyl]benzenesulfonamide

Biological Activity

Glucocorticoid receptor agonist (pIC50 = 8). Inhibits production of the proinflammatory mediator IL-6 in vivo.

Licensing Information

Sold for research purposes under agreement from GlaxoSmithKline.

Technical Data

Soluble to 100 mM in DMSO
>98 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Yates et al (2010) Structure guided design of 5-arylindazole glucocorticoid receptor agonists and antagonists. J.Med.Chem. 53 4531. PMID: 20469868.

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Keywords: GSK 9027, supplier, gsk, GSK9027, glucocorticoid, receptors, agonists, Tocris Bioscience, Glucocorticoid Receptor Agonist products

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