Cat. No. 4116
Chemical Name: N-[4-[1-(4-Fluorophenyl)-1H-indazol
Biological ActivityGlucocorticoid receptor agonist (pIC50 = 8). Inhibits production of the proinflammatory mediator IL-6 in vivo.
Licensing InformationSold for research purposes under agreement from GlaxoSmithKline.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Yates et al (2010) Structure guided design of 5-arylindazole glucocorticoid receptor agonists and antagonists. J.Med.Chem. 53 4531. PMID: 20469868.
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Keywords: GSK 9027, supplier, gsk, GSK9027, glucocorticoid, receptors, agonists, Tocris Bioscience, Glucocorticoid Receptor Agonist products