Oligomycin A

Cat. No. 4110

Oligomycin A C45H74O11 [579-13-5]

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Chemical Name: (1R,4E,5'S,6S,6'S,7R,8S,10R,11R, 12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,9,13-trione

Biological Activity

Inhibitor of mitochondrial ATP synthase and uncoupler of oxidative phosphorylation. Antibiotic; exhibits anti-tumor activity.

Technical Data

M.Wt:
791.06
Formula:
C45H74O11
Solubility:
Soluble to 10 mM in ethanol
Purity:
>95 %
Storage:
Store at -20°C
CAS No:
579-13-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Salomon et al (2001) Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPase. Chem.Biol. 8 71. PMID: 11182320.

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Keywords: Oligomycin A, supplier, OligomycinA, inhibitors, mitochondrial, ATPase, inhibits, oxidative, phosphorylation, antibiotics, Tocris Bioscience, Other ATPase Inhibitor products

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