Cat. No. 4104
Chemical Name: (3aS,4S,6aR)-Hexahydro-2-oxo-N-[2-[
Biological ActivityBiotinylated anandamide analog; acts as a probe for visualizing the accumulation and intracellular trafficking of anandamide. Blocks anandamide uptake (IC50 = 0.5 μM in HaCaT cells); prevents interaction with FAAH, CB1 and TRPV1.
Licensing InformationSold under licence from the University of Rome and the University of Teramo
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Oddi et al (2010) Pitfalls and solutions in assaying anandamide transport in cells. J.Lipid.Res. 51 2435. PMID: 20447929.
Oddi et al (2009) Molecular identification of albumin and Hsp70 as cytosolic anandamide-binding proteins. Chem.Biol. 16 624. PMID: 19481477.
Fezza et al (2008) Characterization of biotin-anandamide, a novel tool for the visualization of anandamide accumulation. J.Lipid.Res. 49 1216. PMID: 18316795.
Oddi et al (2008) Evidence for the intracellular accumulation of anandamide in adiposomes. Cell Mol.Life Sci. 65 840. PMID: 18213445.
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Keywords: MM-22, supplier, MM22, b-AEA, anandamide, biotinylated, analogs, intracellular, accumulation, trafficking, probe, CB1, CB2, cannabinoid, receptors, Tocris Bioscience, Non-selective Cannabinoid products