Mycophenolate mofetil

Cat. No. 4102

Mycophenolate mofetil C23H31NO7 [128794-94-5]

Price and Availability

For Mycophenolate mofetil pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid 2-(4-morpholinyl)ethyl ester

Biological Activity

Immunosuppressant prodrug of mycophenolic acid (MPA) (Cat. No. 1505). Hydrolyzed by esterases to release MPA (a reversible inhibitor of inosine monophosphate dehydrogenase). Used to prevent organ rejection after transplantation. Displays inhibitory activity of lymphocyte functions. Inhibits type 1 collagen expression, enhances MMP-1 expression, and reduces α-smooth muscle actin gene expression.

Technical Data

M.Wt:
433.49
Formula:
C23H31NO7
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
>99 %
Storage:
Store at RT
CAS No:
128794-94-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Roos et al (2007) In vitro evidence for a direct antifibrotic role of the immunosuppressive drug mycophenolate mofetil. J.Pharm.Exp.Ther. 321 583.

Allison and Eugui (1996) Purine metabolism and immunosuppressive effects of mycophenolate mofetil (MMF). Clin.Transplant. 10 77. PMID: 8680053.

If you know of a relevant reference for Mycophenolate mofetil please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses Mycophenolate mofetil from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Mycophenolate mofetil, supplier, immunosuppressant, pro-drug, MMF, inhibits, inosine, monophosphate, dehydrogenase, Tocris Bioscience, Other Dehydrogenase Inhibitor products

Quick Order

Find multiple products by catalog number

divider line

New Product Guide

Spring/Summer 2017

New Product Guide (Spring/Summer 2017)

Our New Product guide highlights over 130 new products added in the first half of 2017. View PDF today.

divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.