Azathioprine

Cat. No. 4099

Azathioprine C9H7N7O2S [446-86-6]

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Chemical Name: 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine

Biological Activity

Purine analog. Blocks DNA replication and the de novo pathway of purine synthesis. Immunosuppressive and anti-inflammatory drug; induces apoptosis in human T-lymphocytes. Prodrug of 6-mercaptopurine (Cat. No. 4103).

Technical Data

M.Wt:
277.26
Formula:
C9H7N7O2S
Solubility:
Soluble to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at -20°C
CAS No:
446-86-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Maltzman and Koretzky (2003) Azathioprine: old drug, new actions. J.Clin.Invest. 111 1122. PMID: 12697731.

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Citations are publications that use Tocris products.

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Keywords: Azathioprine, supplier, Azathioprine, immunosuppressant, inhibits, DNA, synthesis, inhibitors, lymphocyte, purine, analog, Tocris Bioscience, DNA, RNA and Protein Synthesis products

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