Flutamide

Cat. No. 4094

Flutamide C11H11F3N2O3 [13311-84-7]

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Alternative Name: SCH 13521

Chemical Name: 2-Methyl-N-(4-nitro-3-[trifluoromethyl]phenyl)propanamide

Biological Activity

Non-steroidal antiandrogen; competitive antagonist of the androgen receptor. Blocks the biological activity of testosterone (Cat. No. 2822) in vivo.

Technical Data

M.Wt:
276.21
Formula:
C11H11F3N2O3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>99 %
Storage:
Store at RT
CAS No:
13311-84-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Foster et al (2011) Drug safety is a barrier to the discovery and development of new androgen receptor antagonists. Prostate 71 480. PMID: 20878947.

Butcher et al (2007) Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells. Cancer Res. 67 85. PMID: 17210686.

Sufrin and Coffey (1976) Flutamide. Mechanism of action of a new nonsteroidal antiandrogen. Invest.Urol. 13 429. PMID: 1270239.

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Keywords: Flutamide, supplier, androgen, receptors, antagonists, antiandrogen, nonsteroidal, SCH13521, chemotherapeutics, Tocris Bioscience, Androgen Receptor Antagonist products

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