Cat. No. 4076

P7C3 C21H18Br2N2O [301353-96-8]

Price and Availability

For P7C3 pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 3,6-Dibromo-α-[(phenylamino)methyl]-9H-carbazole-9-ethanol

Biological Activity

NAMPT activator. Proneurogenic and neuroprotective. Protects newborn neurons in the dentate gyrus by mitigating cell death. Also enhances learning and memory in aged rats. Orally available and brain penetrant. Also revents doxorubicin-mediated toxicity in osteosarcoma cells and restores intracellular NAD levels.

Technical Data

Soluble to 100 mM in DMSO
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Wang et al (2014) P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage. Cell 158 1324. PMID: 25215490.

Pieper et al (2010) Discovery of a proneurogenic, neuroprotective chemical. Cell 142 39. PMID: 20603013.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses P7C3 from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: P7C3, supplier, P7C3, neuroprotective, neurogenesis, proneurogenic, Tocris Bioscience, NAMPT Activator products

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

VEGF Pathway & Anti-Angiogenic Therapy

Written by N. Ferrara & Y. Crawford

Angiogenesis Life Science Poster

A summary of antiangiogenic therapies targeting the VEGF pathway and the mechanisms of therapy resistance. Request copy today.

divider line

Cancer Metabolism

Taken from the Cancer Guide Edition 3

Cancer Metabolism Life Science Poster

Our Cancer Metabolism poster summarizes the main metabolic pathways in cancer cells, and highlights potential targets for cancer therapeutics. Request copy or view PDF today.

divider line

New Products in this Area

BMS 795311

Potent cholesteryl ester transfer protein (CETP) inhibitor

Perhexiline maleate

Carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor

MS 023 dihydrochloride

Potent and selective type I PRMT inhibitor


Sialic acid analog; sialyltransferase inhibitor


COMT inhibitor; also inhibits transthyretin aggregation

Sign-up for new product e-alerts
divider line

Twitter Updates

Follow @Tocris on Twitter

Follow us on Twitter!

Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.