TCS 2510

Cat. No. 4069

TCS 2510 C21H29N5O2 [346673-06-1]

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Chemical Name: (5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone

Biological Activity

Highly selective EP4 agonist (EC50 = 2.5 nM; Ki = 1.2 nM). Displays no significant binding at other prostaglandin receptors at concentrations up to 14 μM.

Technical Data

M.Wt:
383.49
Formula:
C21H29N5O2
Solubility:
Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml)
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
346673-06-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Billot et al (2003) Discovery of a potent and selective agonist of the prostaglandin EP4 receptor. Bioorg.Med.Chem.Lett. 130 1129.

If you know of a relevant reference for TCS 2510 please let us know.

Citations are publications that use Tocris products. Selected citations for TCS 2510 include:

Liu et al (2012) Prostaglandin E(2) mediates proliferation and chloride secretion in ADPKD cystic renal epithelia. Am J Physiol Renal Physiol 303 F1425. PMID: 22933297.

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Keywords: TCS 2510, supplier, TCS2510, ep4, prostanoid, receptors, selective, agonists, Tocris Bioscience, Prostanoid Receptor Agonist products

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