Cat. No. 4069
Chemical Name: (5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-b
Biological ActivityHighly selective EP4 agonist (EC50 = 2.5 nM; Ki = 1.2 nM). Displays no significant binding at other prostaglandin receptors at concentrations up to 14 μM.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Billot et al (2003) Discovery of a potent and selective agonist of the prostaglandin EP4 receptor. Bioorg.Med.Chem.Lett. 130 1129.
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Citations are publications that use Tocris products. Selected citations for TCS 2510 include:
Liu et al (2012) Prostaglandin E(2) mediates proliferation and chloride secretion in ADPKD cystic renal epithelia. Am J Physiol Renal Physiol 303 F1425. PMID: 22933297.
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Keywords: TCS 2510, supplier, TCS2510, ep4, prostanoid, receptors, selective, agonists, Tocris Bioscience, Prostanoid Receptor Agonist products
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