Cat. No. 4056
Chemical Name: [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,
Biological ActivityBinds and stabilizes microtubules; leads to cell cycle arrest and apoptosis. Displays significant antitumor activity in ovarian and gastric tumors. Prevents microtubule depolymerization and disassembly in the absence of GTP. Exhibits cytotoxic activity.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Ramaswamy and Puhalla (2006) Docetaxel: a tubulin-stabilizing agent approved for the management of several solid tumors. Drugs Today (Barc) 42 265. PMID: 16703123.
Lyseng-Williamson and Fenton (2005) Docetaxel: a review of its use in metastatic breast cancer. Drugs 65 2513. PMID: 16296875.
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Keywords: Docetaxel, supplier, cancer, therapy, antitumor, binds, stabilizes, microtubules, microtubule, stabilizers, chemotherapeutics, Tocris Bioscience, Microtubule products