AC 261066

Cat. No. 4046

AC 261066 C17H20FNO4S [870773-76-5]

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Chemical Name: 4-[4-(2-Butoxyethoxy-)-5-methyl-2-thiazolyl]-2-fluorobenzoic acid

Biological Activity

Potent RARβ2 agonist (pEC50 = 8.1). Selective over RARβ1, RARα and RARγ (pEC50 values are 6.4, 6.2 and 6.3 respectively). More potent and orally available than AC 55649 (Cat. No. 2436).

Technical Data

Soluble to 100 mM in DMSO and to 100 mM in ethanol
>98 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Lund et al (2009) Design, synthesis, and structure-activity analysis of isoform-selective retinoic acid receptor β ligands. J.Med.Chem. 52 1540. PMID: 19239230.

Lund et al (2005) Discovery of a potent, orally available, and isoform-selective retinoic acid β2 receptor agonist. J.Med.Chem. 48 7517. PMID: 16302793.

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Keywords: AC 261066, supplier, AC261066, RAR, retinoic, acid, receptor, agonists, beta, b, β, agonist, Tocris Bioscience, Retinoic Acid Receptor Agonist products

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