Calcifediol

Cat. No. 4036

Calcifediol C27H44O2 [19356-17-3]

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Alternative Names: 25-Hydroxyvitamin D3, Calcidiol

Chemical Name: (εR,1R,3aS,4E,7aR)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-α,α,ε,7a-tetramethyl-1H-indene-1-pentanol

Biological Activity

Prohormone of calcitriol (Cat. No. 2551). Major circulating form of vitamin D. Suppresses PTH synthesis and secretion in bovine parathyroid cells (ED50 = 2 nM).

Technical Data

M.Wt:
400.64
Formula:
C27H44O2
Solubility:
Soluble in DMSO and in ethanol
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
19356-17-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Fedirko et al (2010) Blood 25-hydroxyvitamin D3 concentrations and incident sporadic colorectal adenoma risk: a pooled case-control study. Am.J.Epidemiol. 172 489. PMID: 20650953.

Ritter et al (2006) 25-hydroxyvitamin D3 suppresses PTH synthesis and secretion by bovine parathyroid cells. Kidney Int. 70 654. PMID: 16807549.

Rowling et al (2006) Megalin-mediated endocytosis of vitamin D binding protein correlates with 25-hydroxycholecalciferol actions in human mammary cells. J.Nutr. 136 2754. PMID: 17056796.

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Keywords: Calcifediol, supplier, major, circulating, forms, vitamin, D, cholecalciferol, 25-HydroxyvitaminD3, calcitriol, 1,25-DihydroxyvitaminD3, Tocris Bioscience, Vitamin D Receptor products

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