Org 24598 lithium salt

Cat. No. 4035

Org 24598 lithium salt C19H19F3LiNO3 [722456-08-8]

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Chemical Name: N-Methyl-N-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-glycine lithium salt

Biological Activity

Selective inhibitor of the glial glycine transporter (GlyT1) (pIC50 values are 6.9, <4 and <3 for GlyT1, GABA transporter and Glyt2 respectively).

Technical Data

Soluble to 10 mM in water and to 5 mM in DMSO
>98 %
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Beato (2008) The time course of transmitter at glycinergic synapses onto motoneurons. J.Neurosci. 28 7412. PMID: 18632945.

Bradaia et al (2004) Role of glial and neuronal glycine transporters in the control of glycinergic and glutamatergic synaptic transmission in lamina X of the rat spinal cord. J.Physiol. 559 169. PMID: 15235081.

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Keywords: Org 24598 lithium salt, supplier, Org24598, glial, glycine, transporters, glyt1, selective, inhibitors, inhibits, Tocris Bioscience, Glycine Transporter Inhibitor products

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