Cyclofenil

Cat. No. 3999

Cyclofenil C23H24O4 [2624-43-3]

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Chemical Name: 4,4'-(Cyclohexylidenemethylene)bisphenol 1,1'-diacetate

Biological Activity

Non-steroidal selective estrogen receptor modulator (SERM). Displays higher affinity for estrogen receptor β (ERβ) than for ERα.

Technical Data

M.Wt:
364.43
Formula:
C23H24O4
Solubility:
Soluble to 10 mM in DMSO
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
2624-43-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Kieser et al (2010) Characterization of the pharmacore properties of novel selective estrogen receptor downregulators (SERDs). J.Med.Chem. 53 3320. PMID: 20334372.

Seo et al (2006) Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential PET agents for imaging estrogen receptors in breast cancer. J.Med.Chem. 49 2496. PMID: 16610793.

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Keywords: Cyclofenil, supplier, Non-steroidal, selective, estrogen, receptors, modulators, SERM, ERα, ERβ, Tocris Bioscience, Estrogen and Related Receptor Modulator products

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