Cat. No. 3999

Cyclofenil C23H24O4 [2624-43-3]

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Chemical Name: 4,4'-(Cyclohexylidenemethylene)bisphenol 1,1'-diacetate

Biological Activity

Non-steroidal selective estrogen receptor modulator (SERM). Displays higher affinity for estrogen receptor β (ERβ) than for ERα.

Technical Data

Soluble to 10 mM in DMSO
>99 %
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Kieser et al (2010) Characterization of the pharmacore properties of novel selective estrogen receptor downregulators (SERDs). J.Med.Chem. 53 3320. PMID: 20334372.

Seo et al (2006) Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential PET agents for imaging estrogen receptors in breast cancer. J.Med.Chem. 49 2496. PMID: 16610793.

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View Related Products by Product Action

Keywords: Cyclofenil, supplier, Non-steroidal, selective, estrogen, receptors, modulators, SERM, ERα, ERβ, Tocris Bioscience, Estrogen and Related Receptor Modulator products

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