Cat. No. 3999
Chemical Name: 4,4'-(Cyclohexylidenemethylene)bisph
Biological ActivityNon-steroidal selective estrogen receptor modulator (SERM). Displays higher affinity for estrogen receptor β (ERβ) than for ERα.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Kieser et al (2010) Characterization of the pharmacore properties of novel selective estrogen receptor downregulators (SERDs). J.Med.Chem. 53 3320. PMID: 20334372.
Seo et al (2006) Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential PET agents for imaging estrogen receptors in breast cancer. J.Med.Chem. 49 2496. PMID: 16610793.
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Citations are publications that use Tocris products.
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Keywords: Cyclofenil, supplier, Non-steroidal, selective, estrogen, receptors, modulators, SERM, ERα, ERβ, Tocris Bioscience, Estrogen and Related Receptor Modulator products
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